Cited Applications: IF, WB Species Specificity: human, mouse, rat
Cited Species: bovine, human, mouse, rat
Positive WB detected in: HeLa cells, MCF-7 cells, mouse testis tissue, NIH/3T3 cells, rat testis tissue
Positive IHC detected in: human cervical cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Recommended dilution: WB : 1:500-1:2000 IHC : 1:400-1:1600 Product Information
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. Immunogen Information
Full name: estrogen receptor 1
Calculated molecular weight: 595 aa, 66 kDa
Observed molecular weight: 65-70 kDa
Gene symbol ESR1
Synonyms ER, ER alpha, Era, ERα, ESR, ESR1, ESRA, Estradiol receptor, Estrogen receptor, estrogen receptor 1, NR3A1 Background The estrogen receptor (ESR, ER) is a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. ESR1, also known as ESR or NR3A1, belongs to the nuclear hormone receptor family and NR3 subfamily. It is a nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. ESR1 can activate the transcriptional activity of TFF1.[PMID: 11731608,10970861]
杭州浩克生物
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