Positive IHC detected in: human liver cancer tissue, mouse brain tissue, human kidney tissue, human colon tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in: HepG2 cells, Hela cells
Positive FC detected in: HeLa cells
Recommended dilution: WB : 1:1000-1:4000 IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB IHC : 1:20-1:500 IF : 1:50-1:500 Product Information
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. Immunogen Information Full name: carnitine palmitoyltransferase 1A (liver)
Calculated molecular weight: 88 kDa
Observed molecular weight: 86 kDa
Gene symbol CPT1A
Synonyms CPT I, CPT1, CPT1 L, CPT1A, CPTI L, L CPT1 Background CPT1A, also named as CPT1, CPT1-L and L-CPTI, belongs to the carnitine/choline acetyltransferase family. It is Localized Chromosome 11q13.1-2. Carnitine palmitoyltransferase (CPT) deficiencies are common disorders of mitochondrial fatty acid oxidation. The CPT system is made up of two separate proteins located in the outer (CPT1) and inner (CPT2) mitochondrial membranes. CPT1A is an active forms of related liver-type carnitine palmitoyltransferase I. (PMID: 11001805). CPT1A deficiency presents as recurrent attacks of fasting hypoketotic hypoglycemia. (PMID: 15363638). This antibody can bind the close sequences genes.
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