Cited Applications: IF, IHC, IP, WB Species Specificity: human, mouse, rat, Canine
Cited Species: canine, Drosophila, human, mouse, rat, Xenopus, zebrafish
Positive WB detected in: HEK-293T cells, HeLa cells, Jurkat cells
Positive IP detected in: HeLa cells
Positive IHC detected in: human testis tissue, human prostate cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive FC detected in: HeLa cells
Recommended dilution: WB : 1:1000-1:6000 IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB IHC : 1:50-1:500 Product Information
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. Immunogen Information
Full name: CP110 protein
Calculated molecular weight: 991 aa, 111 kDa
Observed molecular weight: 113 kDa
Gene symbol CP110
Synonyms Centrosomal protein of 110 kDa, CP110, CP110 protein, KIAA0419 Background CP110, also named as CCP110 and KIAA0419, is an 110kDa protein. This gene is different to the gene CEP110 (geneID:11064; CNTRL). CP110 is a centriolar protein that positively regulates centrioleduplication while restricting centriole elongation and ciliogenesis. And it acts as a key negative regulator of ciliogenesis in collaboration with CEP97 by capping the mother centriole thereby preventing cilia formation.
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