Tested Applications: IHC, WB,ELISA Species Specificity: Human
Positive WB detected in: Daudi cells, Raji cells
Positive IHC detected in: human tonsillitis tissue, human lymphoma tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Recommended dilution: WB : 1:1000-1:8000 IHC : 1:50-1:500 Product Information
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. Immunogen Informatio
Full name: CD19 molecule
Calculated molecular weight: 556 aa, 61 kDa
Observed molecular weight: 95 kDa
Gene symbol CD19
Synonyms B lymphocyte antigen CD19, B4, CD19, CD19 molecule, Differentiation antigen CD19, T cell surface antigen Leu 12 Background CD19 is a B cell–specific molecule that controls B cell activation by complexing with the BCR. CD19 is a member of the Ig superfamily and is the dominant component for the signaling complex on B cells that includes CD21, CD81, and CD22. Humans with CD19 deficiency have reduced proliferative responses to BCR stimulation in vitro and mount impaired Ab responses to vaccination.
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