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BDNF兔多克隆抗体

BDNF兔多克隆抗体

一抗 抗体 试剂
  • 价格￥1200
  • 规格50ul
  • 货号HK210043S
  • 单位支
  • 品牌HaoKebio
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HaoKebioHK210043SBDNF兔多克隆抗体50ul支1200


Applications

Tested Applications:
IF, IHC, WB,ELISA

Cited Applications:
IF, IHC, WB
Species Specificity:
Human, mouse, rat

Cited Species:
human, mouse, rat

Positive WB detected in:
C6 cells, SH-SY5Y cells, PC-12 cells

Positive IHC detected in:
human gliomas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Positive IF detected in:
PC-12 cells

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:200-1:800
IF : 1:50-1:500
Product Information

Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.
Immunogen Information

Full name:
brain-derived neurotrophic factor

Calculated molecular weight:
247 aa, 28 kDa

Observed molecular weight:
28-30 kDa


Gene symbol
BDNF

Synonyms
Abrineurin, BDNF
Background
BDNF is a member of the family of neurotrophic factors. It was first explored and purified from pig brain in 1982, and other members of the neurotrophin family were successively discovered. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of BDNF is reduced in both Alzheimer’s and Huntington disease patients. It participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. It also plays a role in the regulation of stress response and in the biology of mood disorders. The BDNF gene is rather complex in its structure and it can express five different mRNA isoforms by alternative splicing, producing 28-37 kDa proteins.

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