Positive IHC detected in: mouse heart tissue, mouse brain tissue, human brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected in: SH-SY5Y cells
Recommended dilution: WB : 1:500-1:1000 IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB IHC : 1:50-1:500 IF : 1:50-1:500 Product Information
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. Immunogen Information Full name: KIAA0652
Calculated molecular weight: 57 kDa
Observed molecular weight: 57-63 kDa Gene symbol KIAA0652
Synonyms ATG13, Autophagy related protein 13, KIAA0652 Background ATG13 is one component protein of the ULK1 complex which is required for autophagosome formation and mitophagy. ATG13 has two nutrient regulatory phosphorylation sites and the phosphorylation status of ATG13 affect regulation of autophagy by modulating enzyme activity and cellular localization of ULK1. Besides, it has been reported the nonautophagic function of ATG13 on cardiac development for ATG13-deficient embryos show myocardial growth defects.(PMID:27387056, 26801615, 26644405)
杭州浩克生物
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