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AIF兔多克隆抗体

AIF兔多克隆抗体

一抗 抗体 试剂
  • 价格￥2800
  • 规格200ul
  • 货号HK210006L
  • 单位支
  • 品牌HaoKebio
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产品参数
资料下载
品牌商品编码商品名称规格单位单价
HaoKebioHK210006LAIF兔多克隆抗体200ul支2800

Applications

Tested Applications:
IF, IHC, WB,ELISA
Species Specificity:
Human

Positive WB detected in:
LNCaP cells, Hela cells, HEK-293 cells, Jurkat cells, K-562 cells, HSC-T6 cells, NIH-3T3 cells, MDCK cells, Pig brain cells

Positive IHC detected in:
human kidney tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Positive IF detected in:
HeLa cells, human kidney tissue

Recommended dilution:
WB : 1:5000-1:50000
IHC : 1:1000-1:4000
IF : 1:200-1:800
Product Information

Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2a

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Aliquoting is unnecessary for -20oC storage.
Immunogen Information

Full name:
apoptosis-inducing factor, mitochondrion-associated, 1

Calculated molecular weight:
609 aa, 66 kDa

Observed molecular weight:
67 kDa, 57 kDa

Gene symbol
AIFM1

Synonyms
AIF, AIFM1, PDCD8
Background
Apoptosis-inducing factor (AIF) is one of the mitochondrial proteins to be released into the cytosol during apoptosis, and it is discovered as the first protein that regulates caspase-independent apoptosis(PMID:20494118). AIF is encoded as a 67 kDa protein that contains a mitochondrial localization signal (MLS) in the N-terminus.It is cleaved from the 62 kDa to the 57 kDa form following ischemic injury and translocated from the mitochondria to the nucleus in a calpain-dependent manner(PMID:19332058).

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