FactorVIII受体兔单克隆抗体

FactorVIII受体兔单克隆抗体

  • 价格¥11812.5
  • 规格1ml
  • 货号HKI0681B
  • 单位
  • 品牌HaoKebio

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HaoKebioHKI0681BFactorVIII受体兔单克隆抗体1ml11812.5

Applications

Tested Applications:
WB,ELISA

Species Specificity:
Human

Positive WB detected in:
human plasma tissue, human blood tissue

Recommended dilution:
WB : 1:1000-1:8000

Product Information


Source:
Mouse

Purification method:
Protein G purification

Isotype:
IgG1

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
coagulation factor VIII, procoagulant component

Calculated molecular weight:
2351 aa, 267 kDa

Observed molecular weight:
70 kDa
 
 

Gene symbol
F8

Synonyms
AHF, Antihemophilic factor, Coagulation factor VIII, DXS1253E, F8, F8B, F8C, FVIII, HEMA, Procoagulant component

Background

F8, also named as AHF and F8C, belongs to the multicopper oxidase family. F8, along with calcium and phospholipid, acts as a cofactor for factor IXa when it converts factor X to the activated form, factor Xa. F8 can be cleaved to 4 chains: F8a heavy chain, 200 kDa isoform, F8a heavy chain, 92 kDa isoform, F8 B chain and F8a light chain. This antibody can recognize the light chain.

Applications

Tested Applications:
IHC,ELISA

Species Specificity:
human

Positive IHC detected in:

human tonsillitis tissue, human lung cancer tissue

Applications

Tested Applications:

IHC, WB, ELISA


Cited Applications:
IF, IHC, WB

Species Specificity:
human, mouse, rat

Cited Species:
human, mouse, rat

Positive WB detected in:
mouse brain tissue, rat brain tissue

Positive IHC detected in:

mouse brain tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Recommended dilution:
WB : 1:2000-1:16000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

 

Full name:
myelin basic protein

Calculated molecular weight:
33 kDa

Observed molecular weight:
17-22 kDa
 
 

Gene symbol
MBP

Synonyms
MBP, Myelin A1 protein, Myelin basic protein

Background

MBP belongs to the myelin basic protein family. The classic group of MBP isoforms (isoform 4-isoform 14) are the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. MBP has six isoforms. Catalog#10458-1-AP is capable of recognizing multiple isoforms of MBP.

Protocols

PRODUCT SPECIFIC PROTOCOLS

 

WB proto

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0


Recommended dilution:
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CD7 molecule

Calculated molecular weight:
240 aa, 25 kDa
 
Gene symbol
CD7

Synonyms
CD7, CD7 molecule, GP40, LEU 9, T cell antigen CD7, T cell leukemia antigen, T cell surface antigen Leu 9, Tp40, TP41

Background

CD7 is a 40 kD type I transmembrane glycoprotein expressed on thymocytes and mature T cells. It is the most reliable clinical marker of T-cell acute lymphocytic leukemia.

 

 

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