MART-1/melanA兔单克隆抗体

品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKI0641A	MART-1/melanA兔单克隆抗体	100ul	支	2888

Applications

Tested Applications:

IHC,ELISA

Species Specificity:

human

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Positive IHC detected in:

human malignant melanoma tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

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Recommended dilution:

IHC : 1:500-1:2000

Product Information

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Source:

Mouse

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Purification method:

Protein A purification

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Isotype:

IgG2a

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Immunogen Information

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Full name:

melan-A

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Calculated molecular weight:

13 kDa

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Observed molecular weight:

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Gene symbol

MLANA

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Synonyms

Antigen LB39 AA, Antigen SK29 AA, MART 1, MART1, melan A, MLANA, Protein Melan A

Background

Melan-A is a melanocyte differentiation antigen, recognized by autologous cytotoxic T lymphocytes. Melan-A is also called MART-1 (melanoma antigen recognized by T cells). The Melan-A/MART-1 gene encodes this protein, 20-22 kDa, associated with endoplasmic reticulum and melanosomes. The function of the protein is unknown. Melan-A, isolated as a melanoma-specific antigen, is a transmembrane protein, which is expressed in skin, retina and the majority of cultured melanocytes as well as in melanomas. Melan A is expressed in more than 85% of melanomas.

Protocols

PRODUCT