CEA兔单克隆抗体

品牌	商品编码	商品名称	规格	单位	单价
HAOKEBIO	HKI0601A	CEA兔单克隆抗体	100ul	支	1088

Applications

Tested Applications:

IHC,ELISA

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Cited Applications:

chIP, IHC, WB

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Species Specificity:

human

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Cited Species:

human

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Positive IHC detected in:

human colon cancer tissue, human appendicitis tissue, human stomach cancer tissue, human lung cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

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Recommended dilution:

IHC : 1:200-1:800

Product Information

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Source:

Rabbit

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Purification method:

Antigen affinity purification

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Isotype:

IgG

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Immunogen Information

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Full name:

carcinoembryonic antigen-related cell adhesion molecule 5

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Calculated molecular weight:

77 kDa

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Observed molecular weight:

Gene symbol

CEACAM5

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Synonyms

Carcinoembryonic antigen, CD66e, CEA, CEACAM5, Meconium antigen 100

Background

Carcinoembryonic antigen (CEA), also known as CEACAM5 or CD66e, is a cell surface glycoprotein belonging to the immunoglobulin superfamily, mainly serving as a cell adhesion molecule mediating intercellular contact by both homophilic and heterophilic binding (PMID: 21731662). CEA inhibits anoikis and plays a role in tumorigenesis and metastasis. CEA has been found to be overexpressed in a wide variety of human cancers, including colon, breast, and lung (PMID: 17167768). CEA is a tumor marker and is routinely exploited for diagnosis.