ATG13鼠单克隆抗体

品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HK510012M	ATG13鼠单克隆抗体	100ul	支	1960

Applications

Tested Applications:

IF, IHC, WB,ELISA

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Species Specificity:

Human, Mouse, Rat, Pig

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Positive WB detected in:

mouse brain tissue, BGC-823 cells, NIH/3T3 cells, pig brain tissue, rat brain tissue

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Positive IHC detected in:

mouse testis tissue, mouse brain tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

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Positive IF detected in:

HEK-293 cells

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Recommended dilution:

WB : 1:1000-1:4000

IHC : 1:50-1:500

IF : 1:50-1:500

Product Information

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Source:

Mouse

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Purification method:

Protein G purification

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Isotype:

IgG1

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Storage:

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage.

Immunogen Information

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Full name:

KIAA0652

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Calculated molecular weight:

57 kDa

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Observed molecular weight:

57 kDa

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Gene symbol

KIAA0652

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Synonyms

ATG13, Autophagy related protein 13, FLJ20698, KIAA0652

Background

ATG13 is one component protein of the ULK1 complex which is required for autophagosome formation and mitophagy. ATG13 has two nutrient regulatory phosphorylation sites and the phosphorylation status of ATG13 affect regulation of autophagy by modulating enzyme activity and cellular localization of ULK1. Besides, it has been reported the nonautophagic function of ATG13 on cardiac development for ATG13-deficient embryos show myocardial growth defects.(PMID:27387056, 26801615, 26644405)