CD99兔单克隆抗体

价格￥600
规格100ul
货号HKZ150131
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150131	CD99兔单克隆抗体	100ul	支	600

CD99
Recombinant Rabbit Monoclonal Antibody Product Datasheet

Catalog# BX50008 Clone# BP6013

Predicted Molecular Wt:
19kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P14209
Background:
CD99 is a type I transmembrane glycoprotein encoded by the CD99 gene and the functions of CD99 in cells in which CD99 was highly expressed have been studied and they were as follows: cell death of thymocytes and T lymphocytes, migration through monocyte endothelial junctions by adhesion and diapedesis, cell-cell adhesion in lymphocytes, maintenance of cellular
morphology in Hodgkin and Reed/Sternberg cells, and recruitment of T cells.

CD99 expression has been reported in many cell types, such ashematopoietic cells, endothelial cells, central nervous system    ependymal cells, thymocytes, granular cells of the ovary, Sertoli cells, and pancreatic islet cells. And in tumors it expressed by   virtually almost all Ewings sarcoma and primitive peripheral neuroectodermal tumors (ES/PNET) and demonstrates strong and diﬀuse membranous staining. Other tumors that mayshow CD99 expression include neuroendocrine carcinomas,
mesenchymal chondrosarcomas, solitary fibrous tumors, synovial sarcomas, vascular tumors, small round blue cell tumors, lymphoblastic lymphoma, acute myeloid leukemia, and myeloid sarcoma.

Studies have shown that CD99 may be a sensitive marker for Ewing’s sarcoma and peripheral neuroectodermal tumors and

Subcellular location:
Membrane
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to CD99 residues within aa85‐C terminal of CD99 was used as an
immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded
sections) analysis of human Ewing’s sarcoma tissue
labelling CD99 with BP6013. Heat mediated antigen
retrieval was performed    using Tris/EDTA buffer pH 9.0

Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1. Gawon Choi, et al. Journal of Pathology and Translational Medicine 2016; 50: 361-368.