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| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| HaoKebio | HKZ150010 | CD21兔单克隆抗体 | 100ul | 支 | 600 |
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# HKZ150010 Clone# BP6015
Predicted Molecular Wt:
113kDa
Purity: ProA affinity purified IgG
Species Cross-reactivity:
Human
Form: Liquid
Applications:
IHC-P
Swissprot ID: P20023
Background:
CD21 also known as complement C3d receptor, Epstein-Barr virus receptor, and complement receptor type 2 (CR2), is a protein that in humans is encoded by the CR2 gene. This protein is involved in the complement system. It bindsto iC3b (inactive
derivative of C3b), C3dg,or C3d. B cells have CR2 receptors on their surfaces, allowing the complement system to play a role in B- cell activation and maturation.
It is expressed by follicular dendritic cells (FDC) and mature B cells, as well as by several types of epithelial cells.
CD21 is useful in the identification of follicular dendritic cell matrix found in normal lymph node and tonsillar tissue, and also useful in identifying abnormal follicular dendritic cell pattern in angioimmunoblastic T-cell lymphoma and follicular T-cell
lymphoma.
Subcellular location:
Membrane
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to CD21 residues within aa933‐C terminal of CD21 was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P: 1:100-1:200
Background References:
1. Barel M, et al. Mol Immunol. 1995 Apr;32(6):389-97.
2. Tanner J, et al. J Virol. 1988 Dec;62(12):4452-64.
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