Cytokeratin 5兔单克隆抗体

价格￥600
规格100ul
货号HKZ150139
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150139	Cytokeratin 5兔单克隆抗体	100ul	支	600

Cytokeratin 5
Recombinant Rabbit Monoclonal Antibody Product Datasheet

Catalog# BX50016 Clone# BP6021

Predicted Molecular Wt:
62kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P13647

Background:
Cytokeratin 5 is a basic protein that is closely related to cytokeratin 6. They share similar tissue distribution and
are found in various proportions in many non-
keratinizing stratified squamous epithelia eg. tongue  mucosa, as well as in basal epithelia of trachea, basal cells of epidermis, hair follicles, sebaceous and sweat glands of skin, luminal cells of the mammary gland,     basal cells of prostate, urothelium, vagina and
endocervical mucosa. Cytokeratins 5 and 6 are also expressed in basal cell epitheliomas, squamous cell
carcinomas of skin, tongue, epiglottis and of the rectal- anal region. Point mutations in the cytokeratin 5 gene
at locus 12q11-q13 can cause various types of epidermolysis bullosa simplex.
Subcellular location:
Cytoplasm
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded
sections) analysis of
human skin tissue labelling cytokeratin 5 with BP6021. Heat mediated antigen
retrieval was performed    using Tris/EDTA buffer pH 9.0
Immunogen:
Synthetic peptide according to the aa490-590 (C-
terminal) of cytokeratin 5 was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1. Mukhopadhyay S., et.al.  Am J Surg Pathol. 2011 Jan; 35(1):15-25.
2.   KargiA, Gurel D., et.al. Appl Immunohistochem Mol Morphol. 2007 Dec; 15(4):415-20.

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