Cytokeratin 19兔单克隆抗体

价格￥600
规格100ul
货号HKZ150140
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150140	Cytokeratin 19兔单克隆抗体	100ul	支	600

Cytokeratin 19
Recombinant Rabbit Monoclonal Antibody Product Datasheet

Catalog# 50017 Clone# BP6022

Predicted Molecular Wt:
44kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P08727

Background:
Cytokeratin 19 is the smallest keratin and is exceptional since it widely lacks the non–helical tail domain typical for all other keratins. It may have evolved from keratinocyte keratins.

Cytokeratin 19 is expressed in most simple epithelia (excluding parenchymatous cells such as hepatocytes, pancreatic acinar
cells, and renal proximal tubular cells), notably in various ductal epithelia, in small and large intestinal epithelium, in gastric
foveolar epithelium, and in mesothelium. Furthermore, it is present in most cells of pseudostratified epithelia and urothelium   as well as in basal cells of non-keratinizing stratified squamous epithelium. In carcinomas, cytokeratin 19 is widely expressed in both adenocarcinomas and squamous cell carcinomas and therefore is not extensively used as an immunohistochemical
marker for carcinoma subtyping.

Cytokeratin 19 is not expressed in most hepatocytes, therefore cytokeratin 19 is useful in the identification of liver metastasis and can be used in a panel with Hepatocyte Specific Antigen.

Subcellular location:
Cytoplasm
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to cytokeratin 19
residues within aa1‐100 of cytokeratin 19 was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded
sections) analysis of human thyroid cancer tissue
labelling cytokeratin 19 with BP6022. Heat
mediated antigen retrieval was performed using
Tris/EDTA buffer pH 9.0
Background References: