杭州浩克生物
MHC Ⅰ兔单克隆抗体
622暂无
查看全文产品介绍
产品参数
资料下载
| 品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
|---|---|---|---|---|---|
| HaoKebio | HKZ150017 | Cytokeratin 19兔单克隆抗体 | 100ul | 支 | 600 |
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# HKZ150017 Clone# BP6022
Predicted Molecular Wt:
44kDa
Purity: ProA affinity purified IgG
Species Cross-reactivity:
Human
Form: Liquid
Applications:
IHC-P
Swissprot ID: P08727
Background:
Cytokeratin 19 is the smallest keratin and is exceptional since it widely lacks the non–helical tail domain typical for all other keratins. It may have evolved from keratinocyte keratins.
Cytokeratin 19 is expressed in most simple epithelia (excluding parenchymatous cells such as hepatocytes, pancreatic acinar
cells, and renal proximal tubular cells), notably in various ductal epithelia, in small and large intestinal epithelium, in gastric
foveolar epithelium, and in mesothelium. Furthermore, it is present in most cells of pseudostratified epithelia and urothelium as well as in basal cells of non-keratinizing stratified squamous epithelium. In carcinomas, cytokeratin 19 is widely expressed in both adenocarcinomas and squamous cell carcinomas and therefore is not extensively used as an immunohistochemical
marker for carcinoma subtyping.
Cytokeratin 19 is not expressed in most hepatocytes, therefore cytokeratin 19 is useful in the identification of liver metastasis and can be used in a panel with Hepatocyte Specific Antigen.
Subcellular location:
Cytoplasm
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to cytokeratin 19
residues within aa1‐100 of cytokeratin 19 was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P: 1:100-1:200
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded
sections) analysis of human thyroid cancer tissue
labelling cytokeratin 19 with BP6022. Heat
mediated antigen retrieval was performed using
Tris/EDTA buffer pH 9.0
Background References:
1. Barroeta JE, et.al,Endocr Pathol. 2006 Fall;17(3):225- 34.2. Schmitt AM, et.al,Am J Surg Pathol. 2007 Nov;31(11):1677-82.
上一篇: Cytokeratin 5兔单克隆抗体下一篇: CDX2兔单克隆抗体
推荐
-
-
-
-
c-Met (Cytoplasmic)兔多克隆抗体
462Applications Product Information Immunogen Information Background
查看全文
您好！请登录