CD68兔单克隆抗体

价格￥600
规格100ul
货号HKZ150154
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150154	CD68兔单克隆抗体	100ul	支	600

CD68
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# HKZ150031 Clone# BP6036
Predicted Molecular Wt:
37kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P34810
Background:
CD68 is a highly glycosylated transmembrane protein which is mainly located in lysosomes. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen
interactions.
CD68 is detected in different types of macrophages of monocyte lineage and also reacts with myeloid precursor cells in the
bone marrow. Positivity is seen in Kupffer cells and histiocytes in normal lymphoid tissue, but also mast cells and microglia. In tumor tissues, it is detected in fibrous-histiocytic tumors, some epithelial neoplasms, epithelioid cells of some malignant
melanomas.
CD68 may be useful for the identification of myelomonocytic and histiocytic tumors.
Subcellular location:
Membrane
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C)
for 30 minutes.
Immunogen:
Synthetic peptide corresponding to CD68 residues
within aa100-200 of CD68 was used as an immunogen.

Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Immunohistochemistry
(Formalin/PFA-fixed
paraffin-embedded
sections analysis of spleen tissue labelling CD68 with BP6036. Heat mediated
antigen retrieval was
performed using Tris/EDTA buffer pH 9.0

Background References:
1.  Kunz-Schughart LA,et.al, Verh Dtsch Ges Pathol. 2003;87:215-23.
2. Sachdev R, et.al, J Cutan Pathol. 2006 May;33(5):353- 60.

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