PAX-2兔单克隆抗体

价格￥1000
规格100ul
货号HKZ150162
单位支
品牌HaoKebio

产品介绍

产品参数

资料下载

品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150162	PAX-2兔单克隆抗体	100ul	支	1000

PAX-2
Recombinant Rabbit Monoclonal Antibody Product Datasheet

Catalog# BX50039 Clone# BP6044

Predicted Molecular Wt:
45kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:  Q02962
Background:
PAX-2 is a member of the PAX family of transcription factors that, together with PAX-8, is involved in the regulation of the organogenesis of the kidney and the Müllerian system.
Among the non-neoplastic tissue, PAX-2 was expressed in glomerular parietal epithelial cells, renal collecting duct cells,
atrophic renal tubular cells, epithelial cells of ovarian surface, fallopian tube, endocervix, endometrium. Among the primary neoplasms, PAX-2 was mainly noted in renal cell carcinoma, carcinomas of Müllerian origin, nephrogenic adenomas.
Recent investigations have indicated that PAX-2 could serve as a useful immunohistochemical marker that can assist in the diagnosis of epithelial tumors of the kidney, as well as some gynecologic (Müllerian) neoplasms.
Subcellular location:
Nucleus
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to PAX-2 residues
within aa300-400 of PAX-2 was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1. Zhai QJ, et.al,Appl Immunohistochem Mol Morphol.
2010 Jul;18(4):323-32.
2. Ordóñez NG, et.al, Adv Anat Pathol. 2012 Nov;19(6):401-9.
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded
sections analysis of
kidney tissue labelling PAX-2 with BP6044.
Heat mediated antigen   retrieval was performed using Tris/EDTA buffer    pH 9.0

HKZ150162_BP6044_PAX2 下载

暂无