CD19兔单克隆抗体

价格￥600
规格100ul
货号HKZ150164
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150164	CD19兔单克隆抗体	100ul	支	600

CD19
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50041 Clone# BP6046
Predicted Molecular Wt:
61kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P15391
Background:
The human CD19 antigen is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily, which initiates a series of biological responses that are likely to be of central importance to B-cell signaling and/or growth regulation and the
development of a humoral immune response.
CD19 is specifically expressed in normal and neoplastic B cells, as well as follicular dendritic cells. In normal tissues, it is
expressed from pre-B cells until the terminal differentiation to plasma cells. And in tumors, its expression is highly conserved   on most B cell tumors. It is expressed in most acute lymphoblastic leukemias (ALL), chronic lymphocytic leukemias (CLL) and B cell lymphomas.
CD19 is one of the most reliable surface biomarker for B cells and the CD19 monoclonal antibodies have been explored for lymphoma therapy.
Subcellular location:
Membrane
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to CD19 residues
within aa456-556 of CD19 was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1. Wang K, et.al, Exp Hematol Oncol. 2012 Nov 29;1(1):36.
2.  Hammer O,et.al, MAbs. 2012 Sep-Oct;4(5):571-7.
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded
sections analysis of
tonsil tissue labelling
CD19 with BP6046. Heat mediated antigen
retrieval was performed using Tris/EDTA buffer    pH 9.0

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