CD23兔单克隆抗体

价格￥600
规格100ul
货号HKZ150167
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150167	CD23兔单克隆抗体	100ul	支	600

CD23
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50044 Clone# BP6049
Predicted Molecular Wt:
36kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P06734
Background:
CD23 antigen is a transmembrane glycoprotein by various hematopoietic cell types and functions as a low-affinity receptor for IgE. CD23 is involved in regulating IgE production and has other potential biologic functions, including promoting the survival    of germinal center B lymphocytes.
CD23 is found in some mature B-cell lymphomas and in Reed-Sternberg cells in Hodgkin disease. Follicular dendritic cells and  some activated B-cells within germinal centers express CD23 in high density and mantle zone B-cells are stained weakly. The   majority of chronic lymphocytic leukemias/small lymphocytic lymphomas are CD23 positive, whereas mantle cell lymphomas are generally negative.
CD23 has been shown to be useful for the differentiation of small lymphocytic lymphomas and mantle cell lymphoma.
Subcellular location:
Membrane
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to CD23 residues
within aa221-321 of CD23 was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1. Olteanu H, et al. Am J Clin Pathol. 2011 Jan;135(1):46- 53.
2. Kumar S, et al. Mod Pathol. 1996 Sep;9(9):925-9.
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded
sections analysis of
tonsil tissue labelling
CD23 with BP6049. Heat mediated antigen
retrieval was performed using Tris/EDTA buffer    pH 9.0

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