Synaptophysin兔单克隆抗体

Synaptophysin克隆抗体

  • 价格¥600
  • 规格100ul
  • 货号HKZ150171
  • 单位
  • 品牌HaoKebio

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HaoKebioHKZ150171Synaptophysin兔单克隆抗体100ul600
Synaptophysin
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50048 Clone#  BP6053
Predicted Molecular Wt:
34kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P08247
Background:
Synaptophysin, also known as the major synaptic vesicle protein p38, is a protein that in humans is encoded by the SYP gene. The exact function of the protein is unknown: it interacts with the essential synaptic vesicle proteinsynaptobrevin, but when the
synaptophysin gene is experimentally inactivated in animals, they still develop and function normally.
Synaptophysin reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas, and gastrointestinal mucosa. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms.
Synaptophysin is expressed independently of other neuronal differentiation markers and may be used as a differentiation marker in tumor diagnosis.
Subcellular location:
Cytoplasm
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to synaptophysin
residues within aa213-313 of synaptophysin was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1. Wiedenmann B, et.al. Proc Natl Acad Sci U S A. 1986 May;83(10):3500-4.
2. Quinn B. Am J Surg Pathol. 1998 May;22(5):550-6.
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded
sections analysis of
glioma tissue labelling synaptophysin with
BP6053. Heat mediated antigen retrieval was
performed using
Tris/EDTA buffer pH 9.0

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