CD1a兔单克隆抗体

价格￥1000
规格100ul
货号HKZ150173
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150173	CD1a兔单克隆抗体	100ul	支	1000

CD1a
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50050 Clone# BP6055
Predicted Molecular Wt:
37kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P06126
Background:
CD1a is a member of the family group 1 CD1 proteins (CD1a, CD1b, and CD1c), which share the capacity to present microbial lipid antigens to T cells.
CD1a is expressed predominantly on Langerhans cells (LCs), it can be expressed by T-cells under certain conditions. Immature
thymocytes express CD1a, as do some T-cells involved in neoplastic conditions such as pre-lymphoblastic lymphomas/leukemias and follicular dendritic cell sarcoma.
CD1a expression on pathogenic Langerhans cells (LCs) in LCH is regarded as a hallmark of this disease and may as a potential target for future therapeutic strategies against inflammatory skin diseases.
Subcellular location:
Membrane
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to CD1a residues     within aa1-100 of CD1a was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1. Hunger RE, et.al, J Clin Invest. 2004 Mar;113(5):701-8.
2. Ji Hyung Kim, et.al, Nature Immunology 17
(10) , pp. 1159-1166.
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded
sections analysis of
esophagus tissue
labelling CD1a with
BP6055. Heat mediated antigen retrieval was
performed using
Tris/EDTA buffer pH 9.0

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