Cytokeratin 6兔单克隆抗体

价格￥600
规格100ul
货号HKZ150183
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150183	Cytokeratin 6兔单克隆抗体	100ul	支	600

Cytokeratin 6
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50060 Clone# BP6065
Predicted Molecular Wt:
60kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P48668
Background:
Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular
keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16.
Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin
appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer rootsheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and     strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell     nests.
Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.
Subcellular location:
Cytoplasm
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to Cytokeratin 6
residues within aa464-564 of  Cytokeratin 6 was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1. R Mollet al. Histochem Cell Biol (2008) 129:705–733.
2. R Mollet al. Cell, Vol. 31, 1 l-24, November 1982.
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded
sections analysis of
esophagus cancer tissue labelling Cytokeratin 6    with BP6065. Heat
mediated antigen
retrieval was performed using Tris/EDTA buffer    pH 9.0

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