Von Willebrand Factor（VWF）兔单克隆抗体

价格￥600
规格100ul
货号HKZ150202
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150202	Von Willebrand Factor（VWF）兔单克隆抗体	100ul	支	600

Von Willebrand Factor (VWF)
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50079 Clone# BP6084
Predicted Molecular Wt:
309kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P04275
Background:
Human von Willebrand factor (VWF,or factor VIII-related antigen) is a 309 kDa multimeric plasma glycoprotein, important in    the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Von Willebrand factor also acts as  a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing itsheterodimeric structure and protecting  it from premature clearance from plasma.
Von Willebrand factor is synthesized by endothelial cells and is reported to be expressed in a number of tumors of vascular
origin. IHC resultsaid in the classification of acute myeloid leukemia FAB type M7, angiosarcoma and epithelioid hemangioendothelioma.
Subcellular location:
Cytoplasm
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to residues within
aa1150-1250 of von Willebrand factor was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1. Weidner N, Semple JP, Welch WR, Folkman J. N Engl J Med 1991,324:1-8.
2. ObermairA, Wanner C, BilgiS,Speiser P, et al. Am J Obstet Gynecol 1998 Feb;178(2):314-319.
Immunohistochemistry
(Formalin/PFA-fixed
paraffin-embedded
sections) analysis of
Cervix labelling VWF with BP6084. Heat mediated    antigen retrieval was
performed using
Tris/EDTA buffer pH 9.0

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