MUM1兔单克隆抗体

价格¥1000
规格100ul
货号HKZ150212
单位支
品牌HaoKebio

产品介绍

产品参数

资料下载

品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150212	MUM1兔单克隆抗体	100ul	支	1000

MUM1
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50089 Clone# BP6094
Predicted Molecular Wt:
52kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:  Q15306
Background:
MUM1 is one of nuclear transcription factors necessary for development and activation of B lymphocytes. MUM1 belongs to the IRF gene family containing at least 10 widely expressed genes with similar DNA binding motif all involved in regulation of cell growth, transformation and induction of apoptosis as well as development of T-cell immune response. The synonym of    MUM1 is Interferon Regulatory Factor 4 (IRF4) .
MUM1 is found mainly in B-cell lymphoma and melanocytic lesions. Significant variation in positivity mainly due to chromosomal translocations involving MUM1 gene among T-cell lymphomas is observed.
MUM1 is useful in a panel with other markers for subclassification of malignant lymphomas and identification of plasma cell differentiation. Particularly MUM1 may be useful for the identification of plasma cell differentiation when morphologic
evidence is lacking and Ig light chains are difficult to interpret.
Subcellular location:
Nucleus
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to residues within C- Term of MUM1 was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1. Grossman A , Hans-Willi Mittrücker, Nicholl J , et al. Genomics, 1996, 37(2):0-233.
2. Gaidano G , Carbone A . LEUKEMIA, 2000, 14(4):563- 566.
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded
sections) analysis of
diffuse large B cell
lymphoma labelling
MUM1 with BP6094.
Heat mediated antigen   retrieval was performed using Tris/EDTA buffer    pH 9.0

HKZ150212_BP6094_MUM1 下载

暂无