- 价格¥1000
- 规格100ul
- 货号HKZ150092
- 单位支
- 品牌HaoKebio
品牌 | 商品编码 | 商品名称 | 规格 | 单位 | 单价 |
---|
HaoKebio | HKZ150092 | EGFR兔单克隆抗体 | 100ul | 支 | 1000 |
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EGFR
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# HKZ150092 Clone# BP6097
Predicted Molecular Wt:
134kDa
Purity: ProA affinity purified IgG
Species Cross-reactivity:
Human
Form: Liquid
Applications:
IHC-P
Swissprot ID: P00533
Background:
EGFR is type I receptor tyrosine kinase with sequence homology toerbB-1, -2, -3, -4. It binds to Epidermal Growth Factor
(EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR
is overexpressed in tumors of breast, brain, bladder, lung, gastric, head, neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Subcellular location:
Cytomembrane
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at 4°C overnight.
Immunogen:
Synthetic peptide corresponding to EGFR residues within aa1050-1150 of EGFR was used as an
immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P: 1:100-1:200
Background References:
1. Brustmann H, et al. Int J Gynecol Pathol. 2011 Jan; 30(1):76-83.
2. VranicS, et al. Hum Pathol. 2010 Nov; 41(11):1617-23.
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded
sections analysis of
lung carcinoma tissue labelling EGFR with
BP6097. Heat mediated antigen retrieval was
performed using
Tris/EDTA buffer pH 9.0
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