FOXP1 Recombinant Rabbit Monoclonal Antibody Product Datasheet Catalog# BX50107 Clone# BP6112 Predicted Molecular Wt: 75kDa Purity: ProA affinity purified IgG Species Cross-reactivity: Human Form: Liquid Applications: IHC-P Swissprot ID: Q9H334 Background: FOXP1 protein plays an important role in the specification and differentiation of lung epithelium, also acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program. FOXP1 is useful in subclassification of DLBCL and a high cutoff (≥80%) for FOXP1 is needed to achieve high specificity for the ABC subtype. Subcellular location: Nucleus Recommended method: Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes. Immunogen: Synthetic peptide corresponding to residues within aa350-450 of FOXP1 was used as an immunogen. Storage Buffer: PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. Storage conditions: -25°C to -18°C Storage instructions: Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles. Recommended Dilutions: IHC-P: 1:100-1:200 Background References: 1. Rodenas-Cuadrado PM etal. J Comp Neurol 526:1235- 1266. 2. Louis Sam Titus ASC etal. J Neurosci 37:6575-6587. Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of tonsil labelling FOXP1 with BP6112. Heat mediated antigen retrieval was performed using Tris/EDTA buffer pH 9.0.
杭州浩克生物
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