CD25兔单克隆抗体

价格¥1000
规格100ul
货号HKZ150239
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150239	CD25兔单克隆抗体	100ul	支	1000

CD25
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50116 Clone# BP6120
Predicted Molecular Wt:
31kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P01589
Background:
CD25,or interleukin 2 (IL2) receptor alpha (IL2RA), and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (CD25) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble CD25 has been
isolated and determined to result from extracellular proteolyisis. CD25 (the p55 chain of the interleukin-2 receptor) is a     marker of activation for a number of cell types, including T cells, B cells, and macrophages. It also appears to be a reliable immunohistochemical marker for the discrimination of neoplastic from normal/reactive mast cells, with potential as a
diagnostic tool in systemic mastocytosis. CD25 is also expressed on hairy cell leukemia.
Subcellular location:
Membrane
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Recombinant fragment corresponding to Human IL-2
Receptor alpha with aa1-250 was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1.   N.A. Azab, et al. Clinical Immunology. 2008 127(2):151–157.
2. Zhang B, et al. Ann Rheum Dis 2008;67:1037-1040.
Immunohistochemistry (Formalin/PFA-fixed
paraffin-embedded
sections) analysis of
colon carcinoma tissue labelling CD25 with
BP6120. Heat mediated antigen retrieval was
performed using
Tris/EDTA buffer pH 9.0

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