Mammaglobin兔单克隆抗体

价格¥1800
规格100ul
货号HKZ150121
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150121	Mammaglobin兔单克隆抗体	100ul	支	1800

Mammaglobin
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# HKZ150121 Clone# BP6125
Predicted Molecular Wt:
10.5kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:  Q13296
Background:
Mammaglobin, 10 kDa, is a cytoplasmic protein,a mammary-specific member of the uteroglobin family. It is related to a family of epithelial secretory proteins that includes prostatein and Clara cell protein.
Mammaglobin occurs in about 80% of breast carcinomas. The extend is generally larger than that of GCDFP-15. Up to 15% of nonbreast carcinomas (such as stomach, lung, colon, hepatobiliary, thyroid, ovarian, and urothelial carcinomas) have been     reported positive, usually only focally.
Mammaglobin is a sensitive and fairly specific marker for breast carcinoma. The panel should also include Gross cystic disease fluid protein-15 and Estrogen receptor alpha.
Subcellular location:
Cytoplasm
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Recombinant fragment corresponding to Human Mammaglobin was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1.  Fanger GR  etal. Tumour Biol 23:212-21 (2002).
2. Han JH  etal. Arch Pathol Lab Med 127:1330-4 (2003).
Immunohistochemistry
(Formalin/PFA-fixed
paraffin-embedded
sections) analysis of
breast carcinoma labelling Mammaglobin with
BP6125. Heat mediated antigen retrieval was
performed using
Tris/EDTA buffer pH 9.0.

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