IgD兔单克隆抗体

价格¥600
规格100ul
货号HKZ150253
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150253	IgD兔单克隆抗体	100ul	支	600

IgD
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50130 Clone# BP6134
Predicted Molecular Wt:
42kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P01880
Background:
Immunoglobulins are produced by cells of the B-lymphocyte lineage. Based on differences in the heavy chain, five
immunoglobulin isotypes are known as IgA, IgG, IgM, IgDand IgE. Human IgD exists in two forms: secreted IgD (secIgD),
present in small amounts in human serum, and membrane-bound IgD (mIgD), present on the surface of mature B cells. MIgD is co-expressed with membrane-bound IgM (mIgM) and plays a major role as an antigenic receptor on the surface of B-
lymphocytes. IgD is expressed in normal and neoplastic mantle B cells. It is absent in most cells of normal splenic marginal zone but present in 30% to 40% of splenic marginal zone lymphomas (MZLs). Additionally, IgD may be a marker for the
identification of nodular lymphocyte predominant hodgkin lymphoma. Antibody to IgD is useful for classification of B-cell derived lymphomas and plasmacytomas.
Subcellular location:
Cytoplasm
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to residues within   aa50-150 of Human IgD was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1. Leong AS, et al., Geenwich Medical Media Ltd. 1999; 217-219.
2. Arnold A, et al., New Eng J Med 1983; 309:1593-1599.
Immunohistochemistry
(Formalin/PFA-fixed
paraffin-embedded
sections analysis of
human tonsil tissue
labelling IgD with BP6134. Heat mediated antigen
retrieval was performed    using Tris/EDTA buffer pH 9.0

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