PAX-5鼠单克隆抗体

价格¥1000
规格100ul
货号HKZ150195
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150195	PAX-5鼠单克隆抗体	100ul	支	1000

PAX-5
Mouse Monoclonal Antibody Product Datasheet
Catalog# HKZ150195   Clone# BPM6172
Predicted Molecular Wt:
42kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:  Q02548
Background:
Pax genes area family of developmental control genes that encode nuclear transcription factors and have been implicated in the control of mammalian development.
PAX-5 is a marker for B-cells, including B-lymphoblastic neoplasms and maturation stage. It is found in most cases of mature   and precursor B-cell non-Hodgkin lymphomas/leukemias. In approximately 97% of cases of classic Hodgkin lymphoma, Reed- Sternberg cells express PAX-5.
The antibody is a useful tool for the identification of pro, pre, and mature B cells and for classification of lymphomas and subclassification of classic Hodgkin’s lymphoma and anaplastic large cell lymphoma of the T and null-cell type.
Subcellular location:
Nucleus
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide corresponding to residues within
aa300 to aa400 of PAX-5 was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1. Abdelrasoul H  etal. Sci Rep 8:1327 (2018).
2. Hijano DR  etal. Sci Rep 8:11034 (2018)
Immunohistochemistry
(Formalin/PFA-fixed
paraffin-embedded
sections) analysis of
Hodgkin’s lymphoma
labelling PAX-5 with
BPM6172. Heat mediated antigen retrieval was
performed using
Tris/EDTA buffer pH 9.0.

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