COL4A5兔单克隆抗体

价格¥600
规格100ul
货号HKZ150352
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150352	COL4A5兔单克隆抗体	100ul	支	600

COL4A5
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50229 Clone# BP6206
Predicted Molecular Wt:
161kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P29400
Background:
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ‘chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen.
Deletions covering the N-terminal regions of COL4A5 and COL4A6, which are localized in a head-to-head manner, are found in the chromosome Xq22.3 centromeric deletion syndrome. This results in a phenotype with features of diffuse leiomyomatosis   and Alport syndrome (DL-ATS).
Subcellular location:
basement membrane
Recommended method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Recombinant fragment with COL4A5. This information is proprietary to Biolynx and/or its suppliers.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage conditions:
-25°C to -18°C
Storage instructions:
Shipped on blue ice. Upon delivery, aliquot, and store at -25°C to -18°C. Avoid freeze / thaw cycles.
Recommended Dilutions:
IHC-P:     1:100-1:200
Background References:
1. Tsugio Seki et al. Histochem Cell Biol (1998) 110:359-366
2. Yoshioka K etal. Am. J. Pathol (1994) . 144: 986-996
Immunohistochemistry
(Formalin/PFA-fixed paraffin- embedded sections) analysis  of human kidney tissue
labelling COL4A5 with BP6206.
Heat mediated antigen
retrieval was performed using Tris/EDTA buffer pH 9.0

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