MCM2 Recombinant Rabbit Monoclonal Antibody Product Datasheet Catalog# BX50243 Clone# BP6220 Predicted Molecular Wt: 102kDa Purity: ProA affinity purified IgG Species Cross-reactivity: Human Form: Liquid Applications: IHC-P Swissprot ID: P49736 Background: MCM2 acts as component of the MCM2-7 complex, also plays a role in terminally differentiated hair cells development of the cochlea and induces cells apoptosis. MCM2 express in all proliferative cells. As a special marker of cell proliferation, It is superior to Ki-67 in precancerous lesions of colon cancer, lung cancer and other epithelial tissues. It is helpful to study malignant mesothelioma and reactive mesothelioma. Subcellular location: Nucleus Recommended Method: Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes. Immunogen: Full length protein corresponding to Human MCM2. Storage Buffer: PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. Storage Conditions: -25°C to -18°C Shipment Instructions: Shipped on blue ice. Upon delivery store at -25°C to – 18°C. Avoid freeze / thaw cycles. Recommended Dilution: IHC-P: 1:100-1:200 Background References: 1. Todorov I.T., Pepperkok R., Philipova R.N., Kearsey S.E.Cell Sci.107:253-265(1994) 2. Gao J., Wang Q., Dong C., Chen S., Qi Y., Liu Y.PLoS ONE10:E0133522-E0133534(2015) Immunohistochemistry (Formalin/PFA-fixed paraffin- embedded sections) analysis of tonsil labelling MCM2 with BP6220.
杭州浩克生物
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