TRPS1兔单克隆抗体

价格¥1800
规格100ul
货号HKZ150377
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150377	TRPS1兔单克隆抗体	100ul	支	1800

TRPS1
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50254 Clone# BP6231
Predicted Molecular Wt:
141kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:  Q9UHF7
Background:
TRPS1 is a transcription factor that was initially discovered as being mutated in Tricho-rhino-phalangeal syndrome, a
craniofacial and skeletal malformation syndrome. TRPS1 recognizes GATA sequences and represses the activation potential of other GATA factors. In addition, TRPS1 binds to the NuRD complex via CHD4 and can repress other key transcription factors
such asp63 and estrogen receptor.
TRPS1 is highly expressed in breast cancer, cervix, esophageal epithelium.
TRPS1 is used as a sensitive and specific marker of breast cancer in pathological diagnosis.
Subcellular location:
Nucleus
Recommended Method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Recombinant protein fragment of TRPS1 was used as an immunogen.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage Conditions:
-25°C to -18°C
Shipment Instructions:
Shipped on blue ice. Upon delivery store at -25°C to -18 °C. Avoid freeze / thaw cycles.
Recommended Dilution:
IHC-P:     1:100-1:200
Background References:
1. Serandour, A.A. et al. (2018) Oncogene 37, 5281-91.
2. Wang, Y. et al. (2018) Oncogenesis 7, 96.
Immunohistochemistry (Formalin/PFA-fixed paraffin-    embedded sections) analysis of breast cancer labelling TRPS1 with BP6231.

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