INSM-1兔单克隆抗体

价格¥1800
规格100ul
货号HKZ150386
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150386	INSM-1兔单克隆抗体	100ul	支	1800

INSM-1
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50263 Clone# BP6240
Predicted Molecular Wt:
53kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:  Q01101
Background:
INSM-1 (insulinoma-associated protein 1), also known as zinc-finger protein IA-1, is a developmentally regulated zinc-finger
transcription factor. It localizes to the nucleus and is expressed in embryonic tissues undergoing neuroendocrine
differentiation. It plays an important role in neuroendocrine development and is required for normal differentiation of pancreatic endocrine cells. Inhibition of INSM-1 results in decreased formation of glucagon and Insulin positive cells.
INSM-1 is not expressed in normal adult tissues but it can be found highly expressed in neuroendocrine tumors. INSM-1 is mainly used in clinical diagnosis of neuroendocrine tumors.
Subcellular location:
Nucleus
Recommended Method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide. This information is proprietary to Biolynx.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage Conditions:
-25°C to -18°C
Shipment Instructions:
Shipped on blue ice. Upon delivery store at -25°C to -18 °C. Avoid freeze / thaw cycles.
Recommended Dilution:
IHC-P:     1:100-1:200
Background References:
1. Chen, C., et al. 2019. Mol. Cancer Res. 17: 1597-1604.
2. Song, R., et al. 2020.Carcinogenesis 41: 326-333.
Immunohistochemistry (Formalin/PFA-fixed paraffin-
embedded sections) analysis of small cell neuroendocrine carcinoma labelling INSM-1 with BP6240.

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