MUM1兔单克隆抗体

价格¥2200
规格100ul
货号HKZ150397
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150397	MUM1兔单克隆抗体	100ul	支	2200

MUM1
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50274 Clone# BP6251
Predicted Molecular Wt:
52kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:  Q15306
Background:
MUM1 is one of nuclear transcription factors necessary for development and activation of B lymphocytes. MUM1 belongs to the IRF gene family containing at least 10 widely expressed genes with similar DNA binding motif all involved in regulation of cell growth, transformation and induction of apoptosis as well as development of T-cell immune response. The synonym of    MUM1 is Interferon Regulatory Factor 4 (IRF4) .
MUM1 is found mainly in B-cell lymphoma and melanocytic lesions. Significant variation in positivity mainly due to chromosomal translocations involving MUM1 gene among T-cell lymphomas is observed.
MUM1 is useful in a panel with other markers for subclassification of malignant lymphomas and identification of plasma cell differentiation. Particularly MUM1 may beuseful for the identification of plasma cell differentiation when morphologic
evidence is lacking and Ig light chains are difficult to interpret.
Subcellular location:
Nucleus
Recommended Method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide. This information is proprietary to Biolynx.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage Conditions:
-25°C to -18°C
Shipment Instructions:
Shipped on blue ice. Upon delivery store at -25°C to -18 °C. Avoid freeze / thaw cycles.
Recommended Dilution:
IHC-P:     1:100-1:200
Background References:
1. Grossman A , Hans-Willi Mittrücker, Nicholl J , et al. Genomics, 1996, 37(2):0-233.
2. Gaidano G , Carbone A . LEUKEMIA, 2000, 14(4):563- 566.
Immunohistochemistry (Formalin/PFA-fixed paraffin-    embedded sections) analysis of human tonsil labelling MUM1 with BP6251.

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