CK5&6 Recombinant Rabbit Monoclonal Antibody Product Datasheet Catalog# BX50275 Clone# BP6252 Predicted Molecular Wt: 62/60kDa Purity: ProA affinity purified IgG Species Cross-reactivity: Human Form: Liquid Applications: IHC-P Swissprot ID: P13647/P02538/P04259/P48668 Background: Cytokeratin 5 is a basic protein that is closely related to cytokeratin 6. They share similar tissue distribution and are found in various proportions in many non-keratinizing stratified squamous epithelia eg. tongue mucosa, as well as in basal epithelia of trachea, basal cells of epidermis, hair follicles, sebaceous and sweat glands of skin, luminal cells of the mammary gland, basal cells of prostate, urothelium, vagina and endocervical mucosa. Cytokeratins 5 and 6 are also expressed in basal cell epitheliomas, squamous cell carcinomas of skin, tongue, epiglottis and of the rectal-anal region. Point mutations in the cytokeratin 5 gene at locus 12q11-q13 can cause various types of epidermolysis bullosa simplex. Subcellular location: Cytoplasmic Recommended Method: Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes. Immunogen: Synthetic peptide. This information is proprietary to Biolynx. Storage Buffer: PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. Storage Conditions: -25°C to -18°C Shipment Instructions: Shipped on blue ice. Upon delivery store at -25°C to -18 °C. Avoid freeze / thaw cycles. Recommended Dilution: IHC-P: 1:100-1:200 Background References: 1. Mukhopadhyay S., et.al. Am J Surg Pathol. 2011 Jan; 35(1):15-25. 2. KargiA, Gurel D., et.al. Appl Immunohistochem Mol Morphol. 2007 Dec; 15(4):415-20. Immunohistochemistry (Formalin/PFA-fixed paraffin- embedded sections) analysis of human cervical cancer labelling CK5&6 with BP6252
杭州浩克生物
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