L1CAM兔单克隆抗体

价格¥2200
规格100ul
货号HKZ150280
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150280	L1CAM兔单克隆抗体	100ul	支	2200

L1CAM
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# HKZ150280 Clone# BP6257
Predicted Molecular Wt:
140kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P32004
Background:
L1CAM,a neural cell adhesion molecule which is involved in the dynamics of cell adhesion and in the generation of
transmembrane signals at tyrosine kinase receptors. During brain development, L1CAM is critical in multiple processes,
including neuronal migration, axonal growth and fasciculation, and synaptogenesis. In the mature brain, L1CAM plays a role in the dynamics of neuronal structure and function, including synaptic plasticity.
L1CAM’s cytoplasmic expression mainly in CNS, PNS and distal renal tubules.
L1CAM has become a marker for evaluating the malignancy and prognosis of ovarian cancer, endometrial cancer, melanoma and other tumors.
Subcellular location:
Cytoplasm
Recommended Method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Synthetic peptide. This information is proprietary to Biolynx.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage Conditions:
-25°C to -18°C
Shipment Instructions:
Shipped on blue ice. Upon delivery store at -25°C to – 18°C. Avoid freeze / thaw cycles.
Recommended Dilution:
IHC-P:     1:100-1:200
Background References:
Schäfer, M. K. E., et al. Neurobiology of Disease, 40(1), 222–237.
Immunohistochemistry (Formalin/PFA-fixed paraffin-
embedded sections) analysis of human Kidney labelling L1CAM with BP6257.

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