Glucagon Recombinant Rabbit Monoclonal Antibody Product Datasheet Catalog# BX50288 Clone# BP6265 Predicted Molecular Wt: 21kDa Purity: ProA affinity purified IgG Species Cross-reactivity: Human Form: Liquid Applications: IHC-P Swissprot ID: P01275 Background: Glucagon plays a key role in glucose metabolism and homeostasis. Glucagon regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. Glucagon is a counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. It plays an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon secreted in the A cells of the islets of Langerhans and L cells throughout the gastrointestinal tract. Glucagon detect glucagon-secreting cells and tumors, such as glucagon tumors. Subcellular location: Cytoplasm Recommended Method: Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes. Immunogen: Recombinant protein fragment of Glucagon was used as an immunogen. This information is proprietary to Biolynx. Storage Buffer: PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. Storage Conditions: -25°C to -18°C Shipment Instructions: Shipped on blue ice. Upon delivery store at -25°C to – 18°C. Avoid freeze / thaw cycles. Recommended Dilution: IHC-P: 1:100-1:200 Background References: 1. PMID: 10605628 2. PMID: 12626323 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human pancrease labelling Glucagon with BP6265.
杭州浩克生物
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