Hemoglobin alpha chain Recombinant Rabbit Monoclonal Antibody Product Datasheet Catalog# BX50290 Clone# BP6267 Predicted Molecular Wt: 14kDa Purity: ProA affinity purified IgG Species Cross-reactivity: Human Form: Liquid Applications: IHC-P Swissprot ID: P69905 Background: Hemoglobin alpha is the main component of human hemoglobin. Hemoglobin alpha is composed of two α globin and two β globin chains. Hemoglobin alpha chain is involved in the transport of oxygen from the lungs to various peripheral tissues. Hemoglobin alpha is expressed in spleen, bone marrow, placenta, kidney and brain. When hemoglobin alpha is low in the human body, it often represents adisease called beta thalassemia. Beta thalassemia is a genetic disorder caused by the loss of the beta peptide chain. There is a decrease in hemoglobin alpha, accompanied by an abnormal increase in hemoglobin F. Subcellular location: Cytoplasm Recommended Method: Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes. Immunogen: Synthetic peptide. This information is proprietary to Biolynx. Storage Buffer: PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. Storage Conditions: -25°C to -18°C Shipment Instructions: Shipped on blue ice. Upon delivery store at -25°C to -18 °C. Avoid freeze / thaw cycles. Recommended Dilution: IHC-P: 1:100-1:200 Background References: 1. Davis JA etal. J Neurotrauma 37:1729-1739 (2020). 2. Strain MM etal. Physiol Behav 212:112695 (2019). Immunohistochemistry (Formalin/PFA-fixed paraffin- embedded sections) analysis of human esophagus labelling Hemoglobin alpha chain with BP6267.
杭州浩克生物
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