Clusterin兔单克隆抗体

价格¥1400
规格100ul
货号HKZ150414
单位支
品牌HaoKebio

产品介绍

产品参数

资料下载

品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150414	Clusterin兔单克隆抗体	100ul	支	1400

Clusterin
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50291 Clone# BP6268
Predicted Molecular Wt:
52kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P10909
Background:
Clusterin functions as extracellular chaperone that prevents aggregation of nonnative proteins. It also functions as
extracellular chaperone that prevents aggregation of nonnative proteins. It’s intracellular form suppresses stress-induced apoptosis by stabilizing mitochondrial membrane integrity through interaction with HSPA5.
Clusterin is detected in blood plasma, cerebrospinal fluid, milk, seminal plasma and colon mucosa.  It’s also detected in brain, testis, ovary, liver and pancreas, and at lower levels in kidney, heart, spleen and lung.
Clusterin has been shown to stain 95% of systemic ALCL, including 100% of ALK-1(+) and 91% of ALK-1(-) ALCL. Studies have shown that clusterin may be a useful diagnostic marker for ALCL, especially in ALK-1(-) cases. Overexpression of clusterin
appears to be a useful prognostic factor for patients with ovarian carcinomas.
Subcellular location:
Secreted
Recommended Method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Recombinant protein fragment of Clusterin was used as an immunogen. This information is proprietary to  Biolynx.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage Conditions:
-25°C to -18°C
Shipment Instructions:
Shipped on blue ice. Upon delivery store at -25°C to – 18°C. Avoid freeze / thaw cycles.
Recommended Dilution:
IHC-P:     1:100-1:200
Background References:
1. PMID:11123922
2. PMID:17322305
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded    sections) analysis of  human ALCL labelling Clusterin with BP6268.

HKZ150414_BP6268_Clusterin 下载

暂无