EZH2兔单克隆抗体

价格¥1400
规格100ul
货号HKZ150415
单位支
品牌HaoKebio

产品介绍

产品参数

资料下载

品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150415	EZH2兔单克隆抗体	100ul	支	1400

EZH2
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# BX50292 Clone# BP6269
Predicted Molecular Wt:
85kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:  Q15910
Background:
EZH2 belongs to polycomb group (PcG). Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates’Lys-9′ (H3K9me) and’Lys-27′ (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. EZH2 displays a
preference for substrates with less methylation. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases.
EZH2 expressed in many tissues. In the ovary, EZH2 expressed in primordial follicles and oocytes and also in external follicle cells. EZH2 overexpressed in numerous tumor types including carcinomas of the breast, colon, larynx, lymphoma and testis.
The high expression of EZH2 is closely related to the malignant process, invasiveness and metastasis ability of tumors. EZH2 may be a new marker and therapeutic target for lymphoma.
Subcellular location:
Nucleus
Recommended Method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Recombinant protein fragment of EZH2 was used as an immunogen. This information is proprietary to Biolynx.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage Conditions:
-25°C to -18°C
Shipment Instructions:
Shipped on blue ice. Upon delivery store at -25°C to – 18°C. Avoid freeze / thaw cycles.
Recommended Dilution:
IHC-P:     1:100-1:200
Background References:
1. PMID: 14532106
2. PMID: 31451685
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of  human testis labelling EZH2 with BP6269.

HKZ150415_BP6269_EZH2 下载

暂无