CD63兔单克隆抗体

价格¥1000
规格100ul
货号HKZ150294
单位支
品牌HaoKebio

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品牌	商品编码	商品名称	规格	单位	单价
HaoKebio	HKZ150294	CD63兔单克隆抗体	100ul	支	1000

CD63
Recombinant Rabbit Monoclonal Antibody Product Datasheet
Catalog# HKZ150294 Clone# BP6271
Predicted Molecular Wt:
26kDa
Purity:   ProA affinity purified IgG
Species Cross-reactivity:
Human
Form:   Liquid
Applications:
IHC-P
Swissprot ID:   P08962
Background:
CD63 Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. It plays a
role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. It promotes
cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration. It also plays a role in intracellular vesicular transport processes.
CD63 is weakly expressed on B and T cells and granulocytes. It’s also expressed in bronchial glands, neural tissue (brain white matter and peripheral nerves), nevi, salivary glands, smooth muscle and synovial lining cells.
CD63 is a marker of melanoma (although non-specific) and melanocytic tumors.
Subcellular location:
Membrane and cytoplasm
Recommended Method:
Heat induced epitope retrieval with Tris-EDTA buffer   (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes.
Immunogen:
Recombinant protein fragment of CD63 was used as an immunogen. This information is proprietary to Biolynx.
Storage Buffer:
PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%.
Storage Conditions:
-25°C to -18°C
Shipment Instructions:
Shipped on blue ice. Upon delivery store at -25°C to – 18°C. Avoid freeze / thaw cycles.
Recommended Dilution:
IHC-P:     1:100-1:200
Background References:
1. PMID: 16917503
2. PMID: 19640571
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded     sections) analysis of  human prostate labelling CD63 with BP6271

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