PSMA Recombinant Rabbit Monoclonal Antibody Product Datasheet Catalog# HKZ150299 Clone# BP6276 Predicted Molecular Wt: 84kDa Purity: ProA affinity purified IgG Species Cross-reactivity: Human Form: Liquid Applications: IHC-P Swissprot ID: Q04609 Background: PSMA is a type II transmembrane protein in the M28 family that combines folate hydrolase and N-acetylation α Associated acid dipeptidase activity. PSMA was originally found in the LNCaP cell line, which originated from lymph node metastasis of prostate cancer. Research studies have shown that PSMA is a well-defined marker for prostate cancer and is also expressed in other tissues such as the kidney, liver, and bladder. PSMA is used as a diagnostic and prognostic indicator of prostate cancer, and as a possible marker for various neurological disorders such as schizophrenia, Alzheimer disease and Huntington disease. Subcellular location: Cytoplasm&Membrane Recommended Method: Heat induced epitope retrieval with Tris-EDTA buffer (pH 9.0), primary antibody incubate at RT (18°C-25°C) for 30 minutes. Immunogen: Synthetic peptide. This information is proprietary to Biolynx. Storage Buffer: PBS 59%, Sodium azide 0.01%, Glycerol 40%, BSA 0.05%. Storage Conditions: -25°C to -18°C Shipment Instructions: Shipped on blue ice. Upon delivery store at -25°C to -18 °C. Avoid freeze / thaw cycles. Recommended Dilution: IHC-P: 1:100-1:200 Background References: 1. Mease, R.C. (2013) Curr Top Med Chem 13, 951-62. 2. Frigerio, B. (2013) Eur J Cancer 49, 2223-32. Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human prostate labelling PSMA with BP6276.
杭州浩克生物
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